Evaluating the Influence of Spatial Resampling for Motion Correction in Resting-State Functional MRI.

ABSTRACT: Head motion is one of major concerns in current resting-state functional MRI studies. Image realignment including motion estimation and spatial resampling is often applied to achieve rigid-body motion correction. While the accurate estimation of motion parameters has been addressed in most studies, spatial resampling could also produce spurious variance, and lead to unexpected errors on the amplitude of BOLD signal. In this study, two simulation experiments were designed to characterize these variance related with spatial resampling. The fluctuation amplitude of spurious variance was first investigated using a set of simulated images with estimated motion parameters from a real dataset, and regions more likely to be affected by spatial resampling were found around the peripheral regions of

SUBMITTER: Yuan L 

PROVIDER: S-EPMC5186805 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature