Ontology highlight
ABSTRACT:
SUBMITTER: Ye X
PROVIDER: S-EPMC5191950 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Ye Xiaojing X Kapeller-Libermann Dana D Travaglia Alessio A Inda M Carmen MC Alberini Cristina M CM
Nature neuroscience 20161121 1
The ability to regulate the consolidation and strengthening of memories for threatening experiences is critical for mental health, and its dysregulation may lead to psychopathologies. Re-exposure to the context in which the threat was experienced can either increase or decrease fear response through distinct processes known, respectively, as reconsolidation or extinction. Using a context retrieval-dependent memory-enhancement model in rats, we report that memory strengthens through activation of ...[more]