Versatile and inexpensive Hall-Effect force sensor for mechanical characterization of soft biological materials.

ABSTRACT: Mismatch of hierarchical structure and mechanical properties between tissue-engineered implants and native tissue may result in signal cues that negatively impact repair and remodeling. With bottom-up tissue engineering approaches, designing tissue components with proper microscale mechanical properties is crucial to achieve necessary macroscale properties in the final implant. However, characterizing microscale mechanical properties is challenging, and current methods do not provide the versatility and sensitivity required to measure these fragile, soft biological materials. Here, we developed a novel, highly sensitive Hall-Effect based force sensor that is capable of measuring mechanical properties of biological materials over wide force ranges (μN to N), allowing its use at all steps in

SUBMITTER: Backman DE 

PROVIDER: S-EPMC5191961 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature