From Genomes to Phenotypes: Traitar, the Microbial Trait Analyzer.

ABSTRACT: The number of sequenced genomes is growing exponentially, profoundly shifting the bottleneck from data generation to genome interpretation. Traits are often used to characterize and distinguish bacteria and are likely a driving factor in microbial community composition, yet little is known about the traits of most microbes. We describe Traitar, the microbial trait analyzer, which is a fully automated software package for deriving phenotypes from a genome sequence. Traitar provides phenotype classifiers to predict 67 traits related to the use of various substrates as carbon and energy sources, oxygen requirement, morphology, antibiotic susceptibility, proteolysis, and enzymatic activities. Furthermore, it suggests protein families associated with the presence of particular phenotypes. Our m

SUBMITTER: Weimann A 

PROVIDER: S-EPMC5192078 | biostudies-literature | 2016 Nov-Dec

REPOSITORIES: biostudies-literature