Neuroanatomical Abnormalities in Violent Individuals with and without a Diagnosis of Schizophrenia.

ABSTRACT: Several structural brain abnormalities have been associated with aggression in patients with schizophrenia. However, little is known about shared and distinct abnormalities underlying aggression in these subjects and non-psychotic violent individuals. We applied a region-of-interest volumetric analysis of the amygdala, hippocampus, and thalamus bilaterally, as well as whole brain and ventricular volumes to investigate violent (n = 37) and non-violent chronic patients (n = 26) with schizophrenia, non-psychotic violent (n = 24) as well as healthy control subjects (n = 24). Shared and distinct volumetric abnormalities were probed by analysis of variance with the factors violence (non-violent versus violent) and diagnosis (non-psychotic versus psychotic), adjusted for substance abuse, age, aca

SUBMITTER: Del Bene VA 

PROVIDER: S-EPMC5193361 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature