Identifying Children at Risk of High Myopia Using Population Centile Curves of Refraction.

ABSTRACT:

Purpose

To construct reference centile curves of refraction based on population-based data as an age-specific severity scale to evaluate their efficacy as a tool for identifying children at risk of developing high myopia in a longitudinal study.

Methods

Data of 4218 children aged 5-15 years from the Guangzhou Refractive Error Study in Children (RESC) study, and 354 first-born twins from the Guangzhou Twin Eye Study (GTES) with annual visit were included in the analysis. Reference centile curves for refraction were constructed using a quantile regression model based on the cycloplegic refraction data from the RESC. The risk of developing high myopia (spherical equivalent ≤ -6 diopters [D]) was evaluated as a diagnostic test using the twin follow-up data.

Results

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SUBMITTER: Chen Y 

PROVIDER: S-EPMC5193395 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature