Initial and sustained brain responses to threat anticipation in blood-injection-injury phobia.

ABSTRACT: Blood-injection-injury (BII) phobia differs from other subtypes of specific phobia in that it is associated with elevated disgust-sensitivity as well as specific autonomic and brain responses during processing of phobia-relevant stimuli. To what extent these features play a role already during threat anticipation is unclear. In the current fMRI experiment, 16 female BII phobics and 16 female healthy controls anticipated the presentation of phobia-specific and neutral pictures. On the behavioral level, anxiety dominated the anticipatory period in BII phobics relative to controls, while both anxiety and disgust were elevated during picture presentation. By applying two different models for the analysis of brain responses to anticipation of phobia-specific versus neutral stimuli, we found ini

SUBMITTER: Brinkmann L 

PROVIDER: S-EPMC5200881 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature