Influence of maternal breast milk ingestion on acquisition of the intestinal microbiome in preterm infants.

ABSTRACT:

Background

The initial acquisition and early development of the intestinal microbiome during infancy are important to human health across the lifespan. Mode of birth, antibiotic administration, environment of care, and nutrition have all been shown to play a role in the assembly of the intestinal microbiome during early life. For preterm infants, who are disproportionately at risk of inflammatory intestinal disease (i.e., necrotizing enterocolitis), a unique set of clinical factors influence the establishment of the microbiome. The purpose of this study was to establish the influence of nutritional exposures on the intestinal microbiome in a cohort of preterm infants early in life.

Results

Principal component analysis of 199 samples from 30 preterm infants (<32 weeks) over t

SUBMITTER: Gregory KE 

PROVIDER: S-EPMC5200970 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature