Bloch-Siegert B₁-Mapping Improves Accuracy and Precision of Longitudinal Relaxation Measurements in the Breast at 3 T.

ABSTRACT: Variable flip angle (VFA) sequences are a popular method of calculating T₁ values, which are required in a quantitative analysis of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI). B₁ inhomogeneities are substantial in the breast at 3 T, and these errors negatively impact the accuracy of the VFA approach, thus leading to large errors in the DCE-MRI parameters that could limit clinical adoption of the technique. This study evaluated the ability of Bloch-Siegert B₁ mapping to improve the accuracy and precision of VFA-derived T₁ measurements in the breast. Test-retest MRI sessions were performed on 16 women with no history of breast disease. T₁ was calculated using the VFA sequence, and

SUBMITTER: Whisenant JG 

PROVIDER: S-EPMC5201175 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature