Selective Landscapes in newt Immune Genes Inferred from Patterns of Nucleotide Variation.

ABSTRACT: Host-pathogen interactions may result in either directional selection or in pressure for the maintenance of polymorphism at the molecular level. Hence signatures of both positive and balancing selection are expected in immune genes. Because both overall selective pressure and specific targets may differ between species, large-scale population genomic studies are useful in detecting functionally important immune genes and comparing selective landscapes between taxa. Such studies are of particular interest in amphibians, a group threatened worldwide by emerging infectious diseases. Here, we present an analysis of polymorphism and divergence of 634 immune genes in two lineages of Lissotriton newts: L. montandoni and L. vulgaris graecus Variation in newt immune genes has been shaped predominan

SUBMITTER: Fijarczyk A 

PROVIDER: S-EPMC5203778 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature