Modulation of recognition memory performance by light requires both melanopsin and classical photoreceptors.

ABSTRACT: Acute light exposure exerts various effects on physiology and behaviour. Although the effects of light on brain network activity in humans are well demonstrated, the effects of light on cognitive performance are inconclusive, with the size, as well as direction, of the effect depending on the nature of the task. Similarly, in nocturnal rodents, bright light can either facilitate or disrupt performance depending on the type of task employed. Crucially, it is unclear whether the effects of light on behavioural performance are mediated via the classical image-forming rods and cones or the melanopsin-expressing photosensitive retinal ganglion cells. Here, we investigate the modulatory effects of light on memory performance in mice using the spontaneous object recognition task. Importantly, we

SUBMITTER: Tam SK 

PROVIDER: S-EPMC5204172 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature