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Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics.

ABSTRACT: 2D black phosphorus (BP) nanomaterials are presented as a delivery platform. The endocytosis pathways and biological activities of PEGylated BP nanosheets in cancer cells are revealed for the first time. Finally, a triple-response combined therapy strategy is achieved by PEGylated BP nanosheets, showing a promising and enhanced antitumor effect.

SUBMITTER: Tao W 

PROVIDER: S-EPMC5205548 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics.

Tao Wei W   Zhu Xianbing X   Yu Xinghua X   Yu Xinghua X   Zeng Xiaowei X   Xiao Quanlan Q   Zhang Xudong X   Ji Xiaoyuan X   Wang Xusheng X   Shi Jinjun J   Shi Jinjun J   Zhang Han H   Mei Lin L  

Advanced materials (Deerfield Beach, Fla.) 20161031 1

2D black phosphorus (BP) nanomaterials are presented as a delivery platform. The endocytosis pathways and biological activities of PEGylated BP nanosheets in cancer cells are revealed for the first time. Finally, a triple-response combined therapy strategy is achieved by PEGylated BP nanosheets, showing a promising and enhanced antitumor effect. ...[more]

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