Treatment of denture-related stomatitis improves endothelial function assessed by flow-mediated vascular dilation.

ABSTRACT:

Introduction

The presence of oral inflammation has recently been linked with the pathogenesis of cardiovascular diseases. While numerous studies have described links between periodontitis and endothelial dysfunction, little is known about the influence of denture-related stomatitis (DRS) on cardiovascular risk. Therefore, the aim of this study was to determine whether the treatment of DRS can lead to improvement of the clinical measures of vascular dysfunction.

Material and methods

The DRS patients were treated with a local oral antifungal agent for 3 weeks. Blood pressure, flow-mediated dilatation (FMD) and nitroglycerine-mediated vascular dilatation (NMD) were measured during three study visits: before treatment, one day and two months after conclusion of antifungal therap

SUBMITTER: Osmenda G 

PROVIDER: S-EPMC5206372 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature