Human exposure to dietary inorganic arsenic and other arsenic species: State of knowledge, gaps and uncertainties.

ABSTRACT: Inorganic arsenic (iAs) is ubiquitous in the environment as arsenite (AsIII) and arsenate (AsV) compounds and biotransformation of these toxic chemicals leads to the extraordinary variety of organoarsenic species found in nature. Despite classification as a human carcinogen based on data from populations exposed through contaminated drinking water, only recently has a need for regulatory limits on iAs in food been recognized. The delay was due to the difficulty in risk assessment of dietary iAs, which critically relies on speciation analysis providing occurrence data for iAs in food - and not simply for total arsenic. In the present review the state of knowledge regarding arsenic speciation in food and diet is evaluated with focus on iAs and human exposure assessment through different diet

SUBMITTER: Cubadda F 

PROVIDER: S-EPMC5207036 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature