Transcription of highly repetitive tandemly organized DNA in amphibians and birds: A historical overview and modern concepts.

ABSTRACT: Tandemly organized highly repetitive DNA sequences are crucial structural and functional elements of eukaryotic genomes. Despite extensive evidence, satellite DNA remains an enigmatic part of the eukaryotic genome, with biological role and significance of tandem repeat transcripts remaining rather obscure. Data on tandem repeats transcription in amphibian and avian model organisms is fragmentary despite their genomes being thoroughly characterized. Review systematically covers historical and modern data on transcription of amphibian and avian satellite DNA in somatic cells and during meiosis when chromosomes acquire special lampbrush form. We highlight how transcription of tandemly repetitive DNA sequences is organized in interphase nucleus and on lampbrush chromosomes. We offer LTR-activa

SUBMITTER: Trofimova I 

PROVIDER: S-EPMC5207375 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature