Development of the Liverpool Adverse Drug Reaction Avoidability Assessment Tool.

ABSTRACT:

Aim

To develop and test a new tool to assess the avoidability of adverse drug reactions that is suitable for use in paediatrics but which is also applicable to a variety of other settings.

Methods

The study involved multiple phases. Preliminary work involved using the Hallas scale and a modification of the existing Hallas scale, to assess two different sets of adverse drug reaction (ADR) case reports. Phase 1 defined, modified and refined a new tool using multidisciplinary teams. Phase 2 involved the assessment of 50 ADR case reports from a prospective study of paediatric inpatients by individual assessors. Phase 3 compared assessments with the new tool for individuals and groups in comparison to the 'gold standard' (the avoidability outcome set by a panel of senior investig

SUBMITTER: Bracken LE 

PROVIDER: S-EPMC5207751 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature