Dietary supplementation with rice bran or navy bean alters gut bacterial metabolism in colorectal cancer survivors.

ABSTRACT:

Scope

Heat-stabilized rice bran (SRB) and cooked navy bean powder (NBP) contain a variety of phytochemicals that are fermented by colonic microbiota and may influence intestinal health. Dietary interventions with these foods should be explored for modulating colorectal cancer risk.

Methods and results

A randomized-controlled pilot clinical trial investigated the effects of eating SRB (30 g/day) or cooked navy bean powder (35 g/day) on gut microbiota and metabolites (NCT01929122). Twenty-nine overweight/obese volunteers with a prior history of colorectal cancer consumed a study-provided meal and snack daily for 28 days. Volunteers receiving SRB or NBP showed increased gut bacterial diversity and altered gut microbial composition at 28 days compared to baseline. Supplementatio

SUBMITTER: Sheflin AM 

PROVIDER: S-EPMC5209300 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature