Predictors of treatment response following aspiration sclerotherapy of hepatic cysts: an international pooled analysis of individual patient data.

ABSTRACT:

Objectives

To identify predictive variables of treatment response following aspiration sclerotherapy of large symptomatic hepatic cysts.

Methods

We collected individual patient data from two tertiary referral centres and included all patients treated with aspiration sclerotherapy of a large (>5 cm), symptomatic hepatic cyst. At six months, clinical response was defined as complete or incomplete. Secondary, suboptimal technical response was defined as lower quartile of cyst reduction. Predictive variables of clinical and technical response were analyzed by logistic regression analysis.

Results

We included 86 patients (58 ± 10 years; female 90 %). Complete clinical response rate was 55 %. Median cyst diameter and volume reduction were 71 % (IQR 50-87 %) and 98 % (IRQ 88

SUBMITTER: Wijnands TF 

PROVIDER: S-EPMC5209423 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature