Ehlers-Danlos syndrome hypermobility type is associated with rheumatic diseases.

ABSTRACT: We retrospectively analyzed electronic medical records of patients with Ehlers-Danlos Syndrome hypermobility type (HEDS), including demographic information, workup, rheumatological diagnoses in order to determine its association with rheumatological conditions. HEDS Patients were stratified according to level of workup received (no additional work (physical exam only) = NWU, limited workup = LWU, comprehensive workup = CWU)). HEDS patients were predominantly female (21:4, F:M). The percentage of patients with at least one rheumatological condition was significantly correlated with level of workup (NWU, 9.2%; LWU, 33.3%, CWU, 67.1%; p-value < 0.0001). The HLA-B27 antigen was more prevalent (p-value < 2.2 × 10^-8) in the CWU HEDS patients (23.9%) than in the general population of t

SUBMITTER: Rodgers KR 

PROVIDER: S-EPMC5209734 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature