Effects of Testosterone Treatment in Older Men.

ABSTRACT:

Background

Serum testosterone concentrations decrease as men age, but benefits of raising testosterone levels in older men have not been established.

Methods

We assigned 790 men 65 years of age or older with a serum testosterone concentration of less than 275 ng per deciliter and symptoms suggesting hypoandrogenism to receive either testosterone gel or placebo gel for 1 year. Each man participated in one or more of three trials--the Sexual Function Trial, the Physical Function Trial, and the Vitality Trial. The primary outcome of each of the individual trials was also evaluated in all participants.

Results

Testosterone treatment increased serum testosterone levels to the mid-normal range for men 19 to 40 years of age. The increase in testosterone levels was associated

SUBMITTER: Snyder PJ 

PROVIDER: S-EPMC5209754 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature