Current status and perspectives of interventional clinical trials for glioblastoma - analysis of ClinicalTrials.gov.

ABSTRACT: The records of 208.777 (100%) clinical trials registered at ClinicalTrials.gov were downloaded on the 19th of February 2016. Phase II and III trials including patients with glioblastoma were selected for further classification and analysis. Based on the disease settings, trials were classified into three groups: newly diagnosed glioblastoma, recurrent disease and trials with no differentiation according to disease setting. Furthermore, we categorized trials according to the experimental interventions, the primary sponsor, the source of financial support and trial design elements. Trends were evaluated using the autoregressive integrated moving average model. Two hundred sixteen (0.1%) trials were selected for further analysis. Academic centers (investigator initiated trials) were recorded

SUBMITTER: Cihoric N 

PROVIDER: S-EPMC5210306 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature