MicroScope in 2017: an expanding and evolving integrated resource for community expertise of microbial genomes.

ABSTRACT: The annotation of genomes from NGS platforms needs to be automated and fully integrated. However, maintaining consistency and accuracy in genome annotation is a challenging problem because millions of protein database entries are not assigned reliable functions. This shortcoming limits the knowledge that can be extracted from genomes and metabolic models. Launched in 2005, the MicroScope platform (http://www.genoscope.cns.fr/agc/microscope) is an integrative resource that supports systematic and efficient revision of microbial genome annotation, data management and comparative analysis. Effective comparative analysis requires a consistent and complete view of biological data, and therefore, support for reviewing the quality of functional annotation is critical. MicroScope allows users to a

SUBMITTER: Vallenet D 

PROVIDER: S-EPMC5210572 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature