Simple statistical models predict C-to-U edited sites in plant mitochondrial RNA.

ABSTRACT:

Background

RNA editing is the process whereby an RNA sequence is modified from the sequence of the corresponding DNA template. In the mitochondria of land plants, some cytidines are converted to uridines before translation. Despite substantial study, the molecular biological mechanism by which C-to-U RNA editing proceeds remains relatively obscure, although several experimental studies have implicated a role for cis-recognition. A highly non-random distribution of nucleotides is observed in the immediate vicinity of edited sites (within 20 nucleotides 5' and 3'), but no precise consensus motif has been identified.

Results

Data for analysis were derived from the the complete mitochondrial genomes of Arabidopsis thaliana, Brassica napus, and Oryza sativa; additionally, a combi

SUBMITTER: Cummings MP 

PROVIDER: S-EPMC521485 | biostudies-literature | 2004 Sep

REPOSITORIES: biostudies-literature