Thoracic aorta calcification but not inflammation is associated with increased cardiovascular disease risk: results of the CAMONA study.

ABSTRACT:

Purpose

Arterial inflammation and vascular calcification are regarded as early prognostic markers of cardiovascular disease (CVD). In this study we investigated the relationship between CVD risk and arterial inflammation (¹⁸F-FDG PET/CT imaging), vascular calcification metabolism (Na¹⁸F PET/CT imaging), and vascular calcium burden (CT imaging) of the thoracic aorta in a population at low CVD risk.

Methods

Study participants underwent blood pressure measurements, blood analyses, and ¹⁸F-FDG and Na¹⁸F PET/CT imaging. In addition, the 10-year risk for development of CVD, based on the Framingham risk score (FRS), was estimated. CVD risk was compared across quartiles of thoracic aorta ¹⁸F-FDG uptake, Na¹⁸F uptake,

SUBMITTER: Blomberg BA 

PROVIDER: S-EPMC5214929 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature