Hepatobiliary scintigraphy may improve radioembolization treatment planning in HCC patients.

ABSTRACT:

Background

Routine work-up for transarterial radioembolization, based on clinical and laboratory parameters, sometimes fails, resulting in severe hepatotoxicity in up to 5% of patients. Quantitative assessment of the pretreatment liver function and its segmental distribution, using hepatobiliary scintigraphy may improve patient selection and treatment planning. A case series will be presented to illustrate the potential of this technique. Hepatocellular carcinoma patients with cirrhosis (Child-Pugh A and B) underwent hepatobiliary scintigraphy pre- and 3 months post-radioembolization as part of a prospective study protocol, which was prematurely terminated because of limited accrual. Included patients were analysed together with their clinical, laboratory and treatment data.

Res

SUBMITTER: Braat MNGJA 

PROVIDER: S-EPMC5215993 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature