Association of atopic dermatitis with smoking: A systematic review and meta-analysis.

ABSTRACT:

Background

Tobacco exposure might be a modifiable risk factor for atopic dermatitis (AD).

Objective

We examine the association between AD and exposure to tobacco smoke.

Methods

We performed a systematic review and meta-analysis of observational studies (n = 86) in MEDLINE, EMBASE, Scopus, and Cochrane Library (1823-2015). Quality of evidence was assessed using the Newcastle-Ottawa Scale (NOS). A meta-analysis was performed using random-effects models to estimate pooled odds ratios (OR). Subset analyses were performed for different ages (children, adult), regions, study designs (cross-sectional, longitudinal), study sizes (<5000, ≥5000), study quality (NOS score <6, ≥6), and amount of smoking (mild, extensive).

Results

A diagnosis of AD was associated with highe

SUBMITTER: Kantor R 

PROVIDER: S-EPMC5216172 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature