Ontology highlight
ABSTRACT:
SUBMITTER: Cordeiro A
PROVIDER: S-EPMC5216777 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Oncotarget 20160701 29
PiwiRNAs, small non-coding RNAs processed by Piwi proteins, are involved in maintaining genome stability in germline cells. Recently, piwiRNA expression has been identified in some tumors. We have examined the potential reactivation of the Piwi/piwiRNA pathway in classical Hodgkin lymphoma (cHL). We found that Piwi proteins and three selected piwiRNAs, including piR-651, were expressed in cHL patients and cell lines, indicating that the Piwi/piwiRNA pathway is active in cHL. Interestingly, low l ...[more]