Regulatory Architecture of Gene Expression Variation in the Threespine Stickleback Gasterosteus aculeatus.

ABSTRACT: Much adaptive evolutionary change is underlain by mutational variation in regions of the genome that regulate gene expression rather than in the coding regions of the genes themselves. An understanding of the role of gene expression variation in facilitating local adaptation will be aided by an understanding of underlying regulatory networks. Here, we characterize the genetic architecture of gene expression variation in the threespine stickleback (Gasterosteus aculeatus), an important model in the study of adaptive evolution. We collected transcriptomic and genomic data from 60 half-sib families using an expression microarray and genotyping-by-sequencing, and located expression quantitative trait loci (eQTL) underlying the variation in gene expression in liver tissue using an interval mapp

SUBMITTER: Pritchard VL 

PROVIDER: S-EPMC5217106 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature