Moebius sequence -a multidisciplinary clinical approach.

ABSTRACT:

Background

Moebius Sequence (MS) is a rare disorder defined by bilateral congenital paralysis of the abducens and facial nerves in combination with various odontological, craniofacial, ophthalmological and orthopaedic conditions. The aetiology is still unknown; but both genetic (de novo mutations) and vascular events in utero are reported. The purpose of present study was through a multidisciplinary clinical approach to examine children diagnosed with Moebius-like symptoms. Ten children underwent odontological, ophthalmological, obstetric, paediatric, orthopaedic, genetic, radiological and photographical evaluation. Five patients maintained the diagnosis of MS according to the diagnostic criteria.

Results

All five patients had bilateral facial and abducens paralysis confirme

SUBMITTER: Pedersen LK 

PROVIDER: S-EPMC5217236 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature