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QUANTILE REGRESSION FOR MIXED MODELS WITH AN APPLICATION TO EXAMINE BLOOD PRESSURE TRENDS IN CHINA.


ABSTRACT: Cardiometabolic diseases have substantially increased in China in the past 20 years and blood pressure is a primary modifiable risk factor. Using data from the China Health and Nutrition Survey we examine blood pressure trends in China from 1991 to 2009, with a concentration on age cohorts and urbanicity. Very large values of blood pressure are of interest, so we model the conditional quantile functions of systolic and diastolic blood pressure. This allows the covariate effects in the middle of the distribution to vary from those in the upper tail, the focal point of our analysis. We join the distributions of systolic and diastolic blood pressure using a copula, which permits the relationships between the covariates and the two responses to share information and enables probabilistic state

SUBMITTER: Smith LB 

PROVIDER: S-EPMC5217786 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature