Association of type 2 diabetes susceptibility loci with peripheral nerve function in a Chinese population with diabetes.

ABSTRACT:

Aims/introduction

Previous studies have suggested a possible relationship between type 2 diabetes mellitus susceptibility loci and diabetic complications. The present study aimed to investigate the associations between type 2 diabetes mellitus loci with peripheral nerve function in a Chinese population with type 2 diabetes mellitus.

Materials and methods

A total of 1,900 type 2 diabetes mellitus patients were recruited in the study. We selected ten single nucleotide polymorphisms (SNPs) from ten type 2 diabetes mellitus susceptibility genes previously confirmed in Chinese patients. Genotyping was carried out by using a MassARRAY Compact Analyzer. Peripheral nerve function was evaluated by nerve conduction studies in all participants. The composite Z-scores for nerve conducti

SUBMITTER: Lu J 

PROVIDER: S-EPMC5217885 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature