High neutrophil-to-lymphocyte ratio is associated with increased carotid artery intima-media thickness in type 2 diabetes.

ABSTRACT:

Aims/introduction

Emerging evidence suggests that the neutrophil-to-lymphocyte ratio (NLR) is a novel potential marker of inflammatory responses. The objective was to evaluate the association between NLR and carotid artery intima-media thickness (cIMT) in type 2 diabetes.

Materials and methods

We carried out a case-control study involving 320 patients with type 2 diabetes, and 250 age-, sex- and body mass index-matched healthy controls who all underwent carotid ultrasonography and took a blood examination. We divided the diabetes patients into two groups according to cIMT: 188 diabetes patients with high cIMT and 132 diabetes patients with low cIMT, and compared baseline characteristics and NLR between the two groups and healthy controls.

Results

The mean NLR was sign

SUBMITTER: Li X 

PROVIDER: S-EPMC5217917 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature