Weight Loss and Mortality in Overweight and Obese Cancer Survivors: A Systematic Review.

ABSTRACT:

Background

Excess adiposity is a risk factor for poorer cancer survival, but there is uncertainty over whether losing weight reduces the risk. We conducted a critical review of the literature examining weight loss and mortality in overweight or obese cancer survivors.

Methods

We systematically searched PubMed and EMBASE for articles reporting associations between weight loss and mortality (cancer-specific or all-cause) in overweight/obese patients with obesity-related cancers. Where available, data from the same studies on non-overweight patients were compared.

Results

Five articles describing observational studies in breast cancer survivors were included. Four studies reported a positive association between weight loss and mortality in overweight/obese survivors, and

SUBMITTER: Jackson SE 

PROVIDER: S-EPMC5218508 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature