Serum vitamin D and sex hormones levels in men and women: The Multi-Ethnic Study of Atherosclerosis (MESA).

ABSTRACT:

Introduction

25-hydroxyvitamin D [25(OH)D] deficiency has been associated with low testosterone levels in men, but there are conflicting reports of its associations with sex hormones in women. Less is known about whether these associations are independent of adiposity and lifestyle factors, and whether they differ by race/ethnicity.

Aim

To examine associations of 25(OH)D concentrations with sex hormone levels.

Methods

Cross-sectional analysis of 3017 men and 2929 women in a multi-ethnic cohort.

Main outcome measures

Testosterone, estradiol, dehydroepiandrosterone (DHEA), sex hormone binding globulin (SHBG), and free testosterone.

Results

The mean (SD) levels of 25(OH)D in men and women were 25.7(10.4) and 26.1(12.0)ng/ml, respectively. In men, after adju

SUBMITTER: Zhao D 

PROVIDER: S-EPMC5218632 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature