Effects of extremely low-frequency electromagnetic field on expression levels of some antioxidant genes in human MCF-7 cells.

ABSTRACT: In the past three decades, study on the biological effects of extremely low-frequency electromagnetic fields (ELF-EMFs) has been of interest to scientists. Although the exact mechanism of its effect is not fully understood, free radical processes has been proposed as a possible mechanism. This study was designed to evaluate the effect of 50-Hz EMFs on the mRNA levels of seven antioxidant genes (CAT, SOD1, SOD2, GSTO1, GSTM3, MSGT1, and MSGT3) in human MCF-7 cells. The EMF exposure patterns were: 1) 5 min field-on/5 min filed-off, 2) 15 min field-on/15 min field-off, 3) 30 min field-on continuously. In all three exposure conditions we tried to have total exposure time of 30 minutes. Control cultures were located in the exposure apparatus when

SUBMITTER: Mahmoudinasab H 

PROVIDER: S-EPMC5219897 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature