Differential Effects of Brain Disorders on Structural and Functional Connectivity.

ABSTRACT: Different measures of brain connectivity can be defined based on neuroimaging read-outs, including structural and functional connectivity. Neurological and psychiatric conditions are often associated with abnormal connectivity, but comparing the effects of the disease on different types of connectivity remains a challenge. In this paper, we address the problem of quantifying the relative effects of brain disease on structural and functional connectivity at a group level. Within the framework of a graph representation of connectivity, we introduce a kernel two-sample test as an effective method to assess the difference between the patients and control group. Moreover, we propose a common representation space for structural and functional connectivity networks, and a novel test statistics to

SUBMITTER: Vega-Pons S 

PROVIDER: S-EPMC5221415 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature