The Association between Foveal Morphology and Macular Pigment Spatial Distribution: An Ethnicity Study.

ABSTRACT:

Purpose

Macular pigment (MP) spatial distribution varies considerably among individuals. We investigated ethnic variations in MP spatial distribution in relation to foveal architecture.

Methods

We measured MP optical density (MPOD) using heterochromatic flicker photometry (MAP test, City, University of London) in 76 white, 80 South Asian and 70 black volunteers (18 to 39 years). MPOD spatial profiles were classified objectively as exponential, ring-like or central dip, based on deviations away from an exponential fit. Measurements including total retinal thickness (RT), inner retinal layer (IRL), inner and outer plexiform layer (IPL and OPL) thickness, foveal width and foveal pit slope were taken from Spectralis SD-OCT (Heidelberg, Germany) scans.

Results

Integrated M

SUBMITTER: Ctori I 

PROVIDER: S-EPMC5221785 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature