Dataset Information

Prevalence of Asthma in School Children on the Arizona-Sonora Border.

ABSTRACT:

Background

Mexican-born children living in the United States have a lower prevalence of asthma than other US children. Although children of Mexican descent near the Arizona (AZ)-Sonora border are genetically similar, differences in environmental exposures might result in differences in asthma prevalence across this region.

Objective

The objective of this study was to determine if the prevalence of asthma and wheeze in these children varies across the AZ-Sonora border.

Methods

The International Study of Asthma and Allergy in Children written and video questionnaires were administered to 1753 adolescents from 5 middle schools: Tucson (school A), Nogales, AZ (schools B, C), and Nogales, Sonora, Mexico (schools D, E). The prevalence of asthma and symptoms was compared, with analyses in the AZ schools limited to self-identified Mexican American students.

Results

Compared with the Sonoran reference school E, the adjusted odds ratio (OR) for asthma was significantly higher in US schools A (OR 4.89, 95% confidence interval [CI] 2.72-8.80), B (OR 3.47, 95% CI 1.88-6.42), and C (OR 4.12, 95% CI 1.78-9.60). The adjusted OR for wheeze in the past year was significantly higher in schools A (OR 2.19, 95% CI 1.20-4.01) and B (OR 2.67, 95% CI 1.42-5.01) on the written questionnaire and significantly higher in A (OR 2.13, 95% CI 1.22-3.75), B (OR 1.95, 95% CI 1.07-3.53), and Sonoran school D (OR 2.34, 95% CI 1.28-4.30) on the video questionnaire compared with school E.

Conclusions

Asthma and wheeze prevalence differed significantly between schools and was higher in the United States. Environmental factors that may account for these differences could provide insight into mechanisms of protection from asthma.

SUBMITTER: Carr TF

PROVIDER: S-EPMC5222738 | biostudies-literature | 2017 Jan - Feb

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Prevalence of Asthma in School Children on the Arizona-Sonora Border.

Carr Tara F TF Beamer Paloma I PI Rothers Janet J Stern Debra A DA Gerald Lynn B LB Rosales Cecilia B CB Van Horne Yoshira Ornelas YO Pivniouk Oksana N ON Vercelli Donata D Halonen Marilyn M Gameros Mercedes M Martinez Fernando D FD Wright Anne L AL

The journal of allergy and clinical immunology. In practice 20160817 1

<h4>Background</h4>Mexican-born children living in the United States have a lower prevalence of asthma than other US children. Although children of Mexican descent near the Arizona (AZ)-Sonora border are genetically similar, differences in environmental exposures might result in differences in asthma prevalence across this region.<h4>Objective</h4>The objective of this study was to determine if the prevalence of asthma and wheeze in these children varies across the AZ-Sonora border.<h4>Methods</ ...[more]

PMID: 27544711

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Project description:BackgroundThe aim of this study was to make an in-depth analysis of the prevalence and co-occurrence in pre-school children of possible asthma and atopic manifestations.MethodsIn Sweden 74%-84% of preschool children, depending on age, attend municipality organised day-care centres. Parents of 5,886 children 1-6 years of age, sampled from day-care centres in 62 municipalities all over Sweden, responded to a postal questionnaire regarding symptoms indicating prevalent possible asthma, allergic rhinitis, eczema, and food, furred pet and pollen allergy and other data in their children. Possible asthma was defined as any of the four criteria wheezing four times or more during the last year, physician diagnosis and current wheezing, ever had asthma and current wheezing, and current use of inhalation steroids, all based on questionnaire responses.ResultsThe overall prevalence of possible asthma was 8.9%, of eczema 21.7%, of rhinitis 8.1%, and of food allergy 6.6%. There was a highly significant co-occurrence between possible asthma and all atopic manifestations, 35.7% having any of the manifestations. Presence of pet allergy was the manifestation showing the closest co-occurrence with presence of possible asthma, presence of pollen allergy with presence of rhinitis, and presence of food allergy with presence of eczema. Assessed from plots of age-specific prevalence of possible asthma, rhinitis, eczema and food allergy, the prevalence of all manifestations increased from one to three years of age and then decreased, except for rhinitis where the prevalence increased until six years of age, indicating no specific ordered sequence.ConclusionsParentally reported possible asthma, eczema and food allergy had a curvilinear prevalence course across age with a maximum at age 3, while rhinitis prevalence increased consistently with age. Co-occurrence between possible asthma and atopic manifestations was common, and some combinations were more common than others, but there was no evidence of a specific ordered onset sequence.

Dataset Information

Prevalence of Asthma in School Children on the Arizona-Sonora Border.

Background

Objective

Methods

Results

Conclusions

Publications

Prevalence of Asthma in School Children on the Arizona-Sonora Border.

Similar Datasets

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