Ring-Opening 1,3-Halochalcogenation of Cyclopropane Dicarboxylates.

ABSTRACT: Donor-acceptor cyclopropanes with two geminal carboxylic esters are reacted with chalcogenyl chlorides and bromides to afford ring-opened products bearing the halogen atoms in the 1-position, adjacent to the donor, and the chalcogenyl residue in the 3-position next to the two acceptor groups. A variety of different donors (e.g., aryl, N, and O) are used. The stereospecificity of the reaction is demonstrated by using a chiral starting material.

SUBMITTER: Wallbaum J 

PROVIDER: S-EPMC5223275 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature