Postdiagnosis Weight Change and Survival Following a Diagnosis of Early-Stage Breast Cancer.

ABSTRACT:

Background

Achieving a healthy weight is recommended for all breast cancer survivors. Previous research on postdiagnosis weight change and mortality had conflicting results.

Methods

We examined whether change in body weight in the 18 months following diagnosis is associated with overall and breast cancer-specific mortality in a cohort of n = 12,590 stage I-III breast cancer patients at Kaiser Permanente using multivariable-adjusted Cox regression models. Follow-up was from the date of the postdiagnosis weight at 18 months until death or June 2015 [median follow-up (range): 3 (0-9) years]. We divided follow-up into earlier (18-54 months) and later (>54 months) postdiagnosis periods.

Results

Mean (SD) age-at-diagnosis was 59 (11) years. A total of 980 women died, 503 fr

SUBMITTER: Cespedes Feliciano EM 

PROVIDER: S-EPMC5224999 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature