Single- and multiple viral respiratory infections in children: disease and management cannot be related to a specific pathogen.

ABSTRACT:

Background

The number of viral pathogens associated with pediatric acute respiratory tract infection (ARI) has grown since the introduction of reverse transcription real-time polymerase chain reaction (RT-PCR) assays. Multiple viruses are detected during a single ARI episode in approximately a quarter of all cases. The clinical relevance of these multiple detections is unclear, as is the role of the individual virus. We therefore investigated the correlation between clinical data and RT-PCR results in children with single- and multiple viral ARI.

Methods

Data from children with ARI were prospectively collected during two winter seasons. RT-PCR testing for 15 viruses was performed in 560 ARI episodes. In the patients with a single-viral etiology, clinical data, laboratory fin

SUBMITTER: Wishaupt JO 

PROVIDER: S-EPMC5225597 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature