Microsecond and nanosecond polyproline II helix formation in aqueous nanodrops measured by mass spectrometry.

ABSTRACT: The 1.5 μs and <400 ns time constants for the formation of polyproline II helix structures in 21 and 16 residue peptides, respectively, are measured using rapid mixing from theta-glass emitters coupled with mass spectrometry. Results from these studies should serve as useful benchmarks for comparison with computational simulation results.

SUBMITTER: Mortensen DN 

PROVIDER: S-EPMC5226856 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature