Ketone production in children with type 1 diabetes, ages 4-14 years, with and without nocturnal insulin pump suspension.

ABSTRACT:

Objective

To compare the frequency of elevated morning blood ketone levels according to age in 4-14 year olds with type 1 diabetes following overnight use of an automated low glucose insulin suspension system, or following control nights when the system was not used.

Research design and methods

For 28 children ages 4-9 years and 54 youth ages 10-14 years, elevation of morning blood ketone levels was assessed using the Precision Xtra Ketone meter following 1155 and 2345 nights, respectively. Repeated measures logistic regression models were used to compare age groups for blood ketone level elevation following control nights (system not activated) and following intervention nights with and without insulin suspension.

Results

Elevated morning blood ketones (≥0.6 mmol/L)

SUBMITTER: Wadwa RP 

PROVIDER: S-EPMC5233607 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature