Developmentally regulated long non-coding RNAs in Xenopus tropicalis.

ABSTRACT: Advances in RNA sequencing technologies have led to the surprising discovery that a vast number of transcripts emanate from regions of the genome that are not part of coding genes. Although some of the smaller ncRNAs such as microRNAs have well-characterized functions, the majority of long ncRNA (lncRNA) functions remain poorly understood. Understanding the significance of lncRNAs is an important challenge facing biology today. A powerful approach to uncovering the function of lncRNAs is to explore temporal and spatial expression profiling. This may be particularly useful for classes of lncRNAs that have developmentally important roles as the expression of such lncRNAs will be expected to be both spatially and temporally regulated during development. Here, we take advantage of our ultra-hi

SUBMITTER: Forouzmand E 

PROVIDER: S-EPMC5233649 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature