Hepatic fibrosis and factors associated with liver stiffness in HIV mono-infected individuals.

ABSTRACT:

Background

Liver disease has become an important cause of morbidity and mortality even in those HIV-infected individuals who are devoid of hepatitis virus co-infection. The aim of this study was to evaluate the degree of hepatic fibrosis and the role of associated factors using liver stiffness measurement in HIV mono-infected patients without significant alcohol intake.

Methods

We performed a cross-sectional study of 101 HIV mono-infected patients recruited prospectively from March 1, 2014 to October 30, 2014 at the Center for HIV, St István and St László Hospital, Budapest, Hungary. To determine hepatic fibrosis, liver stiffness was measured with transient elastography. Demographic, immunologic and other clinical parameters were collected to establish a multivariate model.

SUBMITTER: Sulyok M 

PROVIDER: S-EPMC5234436 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature