Distinctions in Breast Tumor Recurrence Patterns Post-Therapy among Racially Distinct Populations.

ABSTRACT:

Background

Clinical studies have revealed a higher risk of breast tumor recurrence in African-American (AA) patients compared to European-American (EA) patients, contributing to the alarming inequality in clinical outcomes among the ethnic groups. However, distinctions in recurrence patterns upon receiving hormone, radiation, and/or chemotherapy between the races remain poorly characterized.

Methods

We compared patterns and rates (per 1000 cancer patients per 1 year) of recurrence following each form of treatment between AA (n = 1850) and EA breast cancer patients (n = 7931) from a cohort of patients (n = 10504) treated between 2005-2015 at Northside Hospital in Atlanta, GA.

Results

Among patients who received any combination of adjuvant therapy, AA displayed higher o

SUBMITTER: Wright N 

PROVIDER: S-EPMC5234824 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature