Bone mineral content and areal density, but not bone area, predict an incident fracture risk: a comparative study in a UK prospective cohort.

ABSTRACT: We studied a prospective UK cohort of women aged 20 to 80 years, assessed by dual-energy X-ray absorptiometry (DXA) at baseline. Bone mineral content (BMC) and areal bone mineral density (aBMD), but not bone area (BA), at femoral neck, lumbar spine and the whole body sites were similarly predictive of incident fractures.

Background

Low aBMD, measured by DXA, is a well-established risk factor for future fracture, but little is known about the performance characteristics of other DXA measures such as BA and BMC in fracture prediction. We therefore investigated the predictive value of BA, BMC and aBMD for incident fracture in a prospective cohort of UK women.

Methods

In this study, 674 women aged 20-80 years, recruited from four GP practices in Southampton, underwent DXA assessm

SUBMITTER: Curtis EM 

PROVIDER: S-EPMC5238932 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature