Effect of Temporal Changes in Therapeutic Exposure on Self-reported Health Status in Childhood Cancer Survivors.

ABSTRACT:

Background

The effect of temporal changes in cancer therapy on health status among childhood cancer survivors has not been evaluated.

Objective

To compare proportions of self-reported adverse health status outcomes among childhood cancer survivors across 3 decades.

Design

Cross-sectional. (ClinicalTrials.gov: NCT01120353).

Setting

27 North American institutions.

Participants

14 566 adults, who survived for 5 or more years after initial diagnosis (median age, 27 years; range, 18 to 48 years), treated from 1970 to 1999.

Measurements

Patient report of poor general or mental health, functional impairment, activity limitation, or cancer-related anxiety or pain was evaluated as a function of treatment decade, cancer treatment exposure, chronic health co

SUBMITTER: Ness KK 

PROVIDER: S-EPMC5239750 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature