The effect of cigarette smoking on the oral and nasal microbiota.

ABSTRACT:

Background

The goal of the study was to investigate whether cigarette smoking alters oral and nasal microbial diversity, composition, and structure. Twenty-three current smokers and 20 never smokers were recruited. From each subject, nine samples including supra and subgingiva plaque scrapes, saliva, swabs from five soft oral tissue sites, and one nasal swab from both the anterior nares were collected. 16S rRNA V3-V4 region was sequenced for microbial profiles.

Results

We found that alpha diversity was lower in smokers than in nonsmokers in the buccal mucosa, but in other sample sites, microbial diversity and composition were not significantly different by smoking status. Microbial profiles differed significantly among eight oral sites.

Conclusions

This study investig

SUBMITTER: Yu G 

PROVIDER: S-EPMC5240432 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature