Genetics and genomics etiology of nonsyndromic orofacial clefts.

ABSTRACT: Orofacial clefts (OFC) are complex birth defects. Studies using contemporary genomic techniques, bioinformatics, and statistical analyses have led to appreciable advances in identifying the causes of syndromic forms of clefts. This commentary gives an overview of the important cleft gene discoveries found using various genomic methods and tools.

SUBMITTER: Adeyemo WL 

PROVIDER: S-EPMC5241211 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature